|The Brain Simulation Platform "Live Papers"|
Authors: Stefano Masoli* 1, Marialuisa Tognolina* 1, Umberto Laforenza 2, Francesco Moccia 3, Egidio D'Angelo 1,4
Author information: 1 Department of Brain and Behavioral Sciences, University of Pavia, Via Forlanini 6, I-27100, Pavia, Italy, 2 Department of Molecular Medicine, University of Pavia, Via Forlanini 6, I-27100, Pavia, Italy, 3 Department of Biology and Biotechnology, University of Pavia, Via Forlanini 6, I-27100, Pavia, Italy, 4 Brain Connectivity Center, IRCCS Mondino Foundation, Via Mondino 2, I-27100, Pavia, Italy, * Co-Author,
Corresponding author: Egidio D'Angelo ( firstname.lastname@example.org )
Citation: Masoli S.*, Tognolina M.*, Laforenza U., Moccia F., D’Angelo E. Parameter tuning differentiates granule cell subtypes enriching the repertoire of retransmission properties at the cerebellum input stage. Biorxiv 2019.
Data and models: Experimental data and models used in the paper are available at the links reported below, grouped into the following categories:
The morphology for the dendrites and soma is in .asc format. The axon was custom generated using a modified BluePyOpt class.
|Granule cell dend-soma morphology:||archiveDownload|
Use the BSP Neuron As A Service (NaaS) tool to do in silico experiments with the single cell models shown in Fig. 6A of the paper:
> Start by clicking on any button below to run a simulation.
> After entering the NaaS page, click on the "Simulation" tab, adjust the current strength with the appropriate value, and run the simulation by clicking the "Start simulation" button.
> To correctly run a simulation, the temperature need to be set at 32°, the vinit at -70mV and, to match the paper experiments, the positive current injections are: 10, 16 and 22pA.