|The Brain Simulation Platform "Live Papers"|
Authors: Stefano Masoli 1, Alessandra Ottaviani 1, Egidio D'Angelo 1,2
Author information: 1 Department of Brain and Behavioral Sciences, University of Pavia, Via Forlanini 6, I-27100, Pavia, Italy, 2 Brain Connectivity Center, IRCCS Mondino Foundation, Via Mondino 2, I-27100, Pavia, Italy,
Corresponding author: Egidio D'Angelo ( firstname.lastname@example.org )
Citation: Stefano Masoli, Alessandra Ottaviani, Egidio D'Angelo. Cerebellar Golgi cell models predict dendritic processing and mechanisms of synaptic plasticity. Biorxiv 2020.
Electrophysiological data available in the HBP Knowledge Graph and are listed below:
Whole cell patch-clamp recordings of cerebellar Golgi cells
Recordings of cerebellar neuronal firing induced by currents steps
Investigation of spatial distribution of excitation in cerebellar cortical slices
Characterization of spatial distribution of activity in cerebellar cortical slices
Recordings of spontaneous firing of cerebellar interneurons (Golgi cells)
One of the models used in the paper is available at the links reported below. Relevant files are grouped by category:
The morphology for the dendrites and the soma is in .asc format. Modified from neuromorpho.org
|Golgi cell morphology 1:||archiveDownload|
Use the BSP Neuron As A Service (NaaS) tool to do in silico experiments with the single cell models shown in Fig. 1C,1D,3A,3B of the paper:
> Start by clicking on any button below to run a simulation.
> After entering the NaaS page, click on the "Simulation" tab, adjust the current strength with the appropriate value, and run the simulation by clicking the "Start simulation" button.
> To correctly run a simulation, the temperature need to be set at 32°, the vinit at -70mV and, to match the paper experiments, and fixed time step at 0.025. Valid positive current injections are from 0.1 to 1nA.