Technique

https://openminds.ebrains.eu/controlledTerms/Technique

part of controlledTerms in version v1 - view as JSON Schema

Required properties are highlighted in bold
propertyvalue
name*descriptiontypeinstruction
name Word or phrase that constitutes the distinctive designation of a being or thing. string Controlled term originating from a defined terminology.
definition Short, but precise statement of the meaning of a word, word group, sign or a symbol. string Enter one sentence for defining this term.
description Longer statement or account giving the characteristics of someone or something. string Enter a short text describing this term.
interlexIdentifier Persistent identifier for a term registered in the InterLex project. string (format: iri) Enter the internationalized resource identifier (IRI) pointing to the integrated ontology entry in the InterLex project.
knowledgeSpaceLink Persistent link to an encyclopedia entry in the Knowledge Space project. string (format: iri) Enter the internationalized resource identifier (IRI) pointing to the wiki page of the corresponding term in the KnowledgeSpace.
preferredOntologyIdentifier Persistent identifier of a preferred ontological term. string (format: iri) Enter the internationalized resource identifier (IRI) pointing to the preferred ontological term.
synonym Words or expressions used in the same language that have the same or nearly the same meaning in some or all senses. array (1 - n) of type:
string
Enter one or several synonyms (including abbreviations) for this controlled term.
*This is the simplified property name - within a metadata instance of this schema (JSON-LD) the properties are extended to map to the openMINDS vocabulary namespace ("https://openminds.ebrains.eu/vocab/PROPERTY_NAME").
instances
nameID Preferred ontology identifier
3D computer graphic modeling https://openminds.ebrains.eu/instances/technique/3DComputerGraphicModeling JSON-LD
3D polarized light imaging '3D polarized light imaging' (synonym: 3D-PLI) is a 3D reconstruction process of high-resoluted image data originating from polorized light microscopy. https://openminds.ebrains.eu/instances/technique/3DPolarizedLightImaging JSON-LD
3D scanning https://openminds.ebrains.eu/instances/technique/3DScanning JSON-LD
4-points congruent sets alignment 4-points congruent sets alignment is a fast and robust alignment technique for 3D point sets without pre-filtering or denoising the data, even if the data are noisy and/or contaminated with outliers ([Aiger et al., 2008](https://doi.org/10.1145/1360612.1360684)). https://openminds.ebrains.eu/instances/technique/4PointsCongruentSetsAlignment JSON-LD
activation likelihood estimation An 'activation likelihood estimation' is a coordinate-based meta-analysis of neuroimaging data that determines the above-chance convergence of activation probabilities between experiments (i.e., not between foci). [adapted from [Eickhoff et al., 2011](https://dx.doi.org/10.1016%2Fj.neuroimage.2011.09.017)] https://openminds.ebrains.eu/instances/technique/activationLikelihoodEstimation JSON-LD
activity modulation technique https://openminds.ebrains.eu/instances/technique/activityModulationTechnique JSON-LD
affine image registration A 'affine image registration' is a process of bringing a set of images into the same coordinate system using affine transformation. https://openminds.ebrains.eu/instances/technique/affineImageRegistration JSON-LD
affine transformation An 'affine transformation' is a specific linear transformation using combinations of rotations, translations, reflections, scaling and shearing to map coordinates between two coordinate spaces. https://openminds.ebrains.eu/instances/technique/affineTransformation JSON-LD
anaesthesia administration https://openminds.ebrains.eu/instances/technique/anaesthesiaAdministration JSON-LD
anaesthesia monitoring https://openminds.ebrains.eu/instances/technique/anaesthesiaMonitoring JSON-LD
anaesthesia technique https://openminds.ebrains.eu/instances/technique/anaesthesiaTechnique JSON-LD
anatomical delineation technique An anatomical delineation technique is any process that identifies the boundaries of an anatomical entity and applies those boundaries to specific data. https://openminds.ebrains.eu/instances/technique/anatomicalDelineationTechnique JSON-LD
anterograde tracing Anterograde tracing is a technique used to trace axonal projections from their source (the cell body or soma) to their point of termination (the synapse). https://openminds.ebrains.eu/instances/technique/anterogradeTracing JSON-LD
autoradiography 'Autoradiography' is a photography technique that creates images of a radioactive source (e.g., molecules or fragments of molecules that have been radioactively labeled) by the direct exposure to an imaging media (e.g., X-ray film or nuclear emulsion) https://openminds.ebrains.eu/instances/technique/autoradiography JSON-LD , Interlex
average linkage clustering https://openminds.ebrains.eu/instances/technique/averageLinkageClustering JSON-LD
avidin-biotin complex staining https://openminds.ebrains.eu/instances/technique/avidinBiotinComplexStaining JSON-LD
beta-galactosidase staining https://openminds.ebrains.eu/instances/technique/beta-galactosidaseStaining JSON-LD
bias field correction A 'bias field correction' is a mathematical technique to remove a corrupting, low frequency signal from magnetic resonance images. This bias field signal is typically caused by inhomogeneities in the magnetic fields of the magnetic resonance imaging machine. https://openminds.ebrains.eu/instances/technique/biasFieldCorrection JSON-LD
biocytin staining In 'biocytin staining' the chemical compound biocytin is used to highlight morphological details of nerve cells. https://openminds.ebrains.eu/instances/technique/biocytinStaining JSON-LD
blood sampling 'Blood sampling' is the process of obtaining blood from a body for purpose of medical diagnosis and/or evaluation of an indication for treatment, further medical tests or other procedures. https://openminds.ebrains.eu/instances/technique/bloodSampling http://purl.obolibrary.org/obo/OBI_1110095 JSON-LD , Interlex
bootstrapping https://openminds.ebrains.eu/instances/technique/bootstrapping JSON-LD
boundary-based registration The term 'boundary-based registration' refers to feature based image registration methods which utilize a boundary which can be identified in the source and target image. https://openminds.ebrains.eu/instances/technique/boundaryBasedRegistration JSON-LD
brightfield microscopy Brightfield microscopy is an optical microscopy techniques, in which illumination light is transmitted through the sample and the contrast is generated by the absorption of light in dense areas of the specimen. https://openminds.ebrains.eu/instances/technique/brightfieldMicroscopy http://uri.interlex.org/tgbugs/uris/indexes/ontologies/methods/238 JSON-LD , Interlex
calcium imaging https://openminds.ebrains.eu/instances/technique/calciumImaging JSON-LD
callosotomy https://openminds.ebrains.eu/instances/technique/callosotomy JSON-LD
cell attached patch clamp 'Cell-attached patch clamp' is an intracellular electrophysiology technique that fully preserves the intracellular integrity by forming a megaohm or gigaohm seal, leaving the cell membrane intact. https://openminds.ebrains.eu/instances/technique/cellAttachedPatchClamp JSON-LD
CLARITY/TDE https://openminds.ebrains.eu/instances/technique/CLARITY_TDE JSON-LD
cluster analysis https://openminds.ebrains.eu/instances/technique/clusterAnalysis JSON-LD
combined volume–surface registration The term 'combined volume-surface registration' refers to an image registration framework which utilizes information from the brain surface and the brain volume to perform the registration (cf. [Postelnicu et al. (2009)](https://doi.org/10.1109/TMI.2008.2004426)). https://openminds.ebrains.eu/instances/technique/combinedVolumeSurfaceRegistration JSON-LD
communication profiling https://openminds.ebrains.eu/instances/technique/communicationProfiling JSON-LD
computer tomography 'Computer tomogoraphy' is a noninvasive medical imaging technique where a computer generates multiple X-ray scans to obtain detailed internal 3D image of the body. https://openminds.ebrains.eu/instances/technique/computerTomography JSON-LD
confocal microscopy Confocal microscopy is a specialized fluorescence microscopy technique that uses pinholes to reject out-of-focus light. https://openminds.ebrains.eu/instances/technique/confocalMicroscopy http://uri.interlex.org/tgbugs/uris/indexes/ontologies/methods/157 JSON-LD , Interlex
conjunction analysis https://openminds.ebrains.eu/instances/technique/conjunctionAnalysis JSON-LD
connected-component analysis 'connected-component analysis' is an algorithmic application of graph theory, where subsets of connected components are uniquely labeled based on a given heuristic. [adapted from: [wikipedia](https://en.wikipedia.org/wiki/Connected-component_labeling)] https://openminds.ebrains.eu/instances/technique/connected-componentAnalysis JSON-LD
connectivity based parcellation technique https://openminds.ebrains.eu/instances/technique/connectivityBasedParcellationTechnique JSON-LD
contrast agent administration A 'contrast agent administration' is a (typically) oral or intraveneous administration of a chemical compound to improve the visibility of internal body structures of a subject in a subsequent imaging technique. https://openminds.ebrains.eu/instances/technique/contrastAgentAdministration JSON-LD
contrast enhancement https://openminds.ebrains.eu/instances/technique/contrastEnhancement JSON-LD
convolution In functional analysis, 'convolution' is a mathematical operation on two functions (f and g) producing a third function (f * g) that expresses how the shape of one is modified by the other. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Convolution)] https://openminds.ebrains.eu/instances/technique/convolution JSON-LD
correlation analysis https://openminds.ebrains.eu/instances/technique/correlationAnalysis JSON-LD
cortico-cortical evoked potential mapping Cortico-cortical evoked potential (CCEP) mapping is used to identify the effective connectivity between distinct neuronal populations based on multiple CCEP measurements across (parts of) the brain in response to direct electrical stimulation (typically at various locations). https://openminds.ebrains.eu/instances/technique/cortico-corticalEvokedPotentialMapping JSON-LD
covariance analysis https://openminds.ebrains.eu/instances/technique/covarianceAnalysis JSON-LD
craniotomy https://openminds.ebrains.eu/instances/technique/craniotomy JSON-LD
cryosectioning Cutting of specimen in cryo/freezing conditions typcially resulting in micromillimeter thin slices. https://openminds.ebrains.eu/instances/technique/cryosectioning JSON-LD
current clamp Current clamp is a technique in which the amount of current injected into the cell is controlled, which allows for the detection of changes in the transmembrane voltage resulting from ion channel activity. https://openminds.ebrains.eu/instances/technique/currentClamp JSON-LD
current source density analysis https://openminds.ebrains.eu/instances/technique/currentSourceDensityAnalysis JSON-LD
cytoarchitectonic mapping 'Cytoarchitectonic mapping' is a delineation technique that defines regional borders based on histological analysis of the cellular composition of the studied tissue. https://openminds.ebrains.eu/instances/technique/cytoarchitectonicMapping JSON-LD
DAB staining In a 'DAB staining', the organic compound DAB (3, 3'-diaminobenzidine) is oxidized in presence of peroxidase and hydrogen peroxide resulting in deposition of a brown, alcohol-insoluble precipitate which can be used in immunohistochemical and blotting applications. https://openminds.ebrains.eu/instances/technique/DABStaining JSON-LD
DAPi staining A nuclear-specific staining technique where DAPi (4′,6-diamidino-2-phenylindole) is used as a dye. https://openminds.ebrains.eu/instances/technique/DAPiStaining JSON-LD
deep learning https://openminds.ebrains.eu/instances/technique/deepLearning JSON-LD
density measurement https://openminds.ebrains.eu/instances/technique/densityMeasurement JSON-LD
dictionary learning 'Dictionary learning' is a branch of signal processing and machine learning that aims at finding a frame (called dictionary) in which some training data admits a sparse representation. https://openminds.ebrains.eu/instances/technique/dictionaryLearning JSON-LD
diffeomorphic registration 'Diffeomorphic registration' refers to a suite of algorithms that register or build correspondences between dense coordinate systems in medical imaging by ensuring the solutions are diffeomorphic. https://openminds.ebrains.eu/instances/technique/diffeomorphicRegistration JSON-LD
diffusion fixation technique Diffusion fixation is a fixation technique to preserve specimen permanently as faithfully as possible compared to the living state by submerging specimen in a fixative. https://openminds.ebrains.eu/instances/technique/diffusionFixationTechnique JSON-LD
diffusion tensor imaging https://openminds.ebrains.eu/instances/technique/diffusionTensorImaging JSON-LD
diffusion-weighted imaging https://openminds.ebrains.eu/instances/technique/diffusionWeightedImaging JSON-LD
DNA methylation analysis A 'DNA methylation analysis' studies chromosomal patterns of DNA or histone modification by methyl groups ([modified from Nature.com](https://www.nature.com/subjects/methylation-analysis)). https://openminds.ebrains.eu/instances/technique/DNAMethylationAnalysis JSON-LD , Interlex
DNA sequencing 'DNA sequencing' refers to a group of techniques that are used to determine the order of nucleotides (nucleic acid sequence) in DNA. [adapted from [wikipedia](https://en.wikipedia.org/wiki/DNA_sequencing)] https://openminds.ebrains.eu/instances/technique/DNASequencing http://purl.obolibrary.org/obo/OBI_0000626 JSON-LD , Interlex
dual-view inverted selective plane illumination microscopy Dual-view inverted selective plane illumination microscopy is a specialized light sheet microscopy technique that allows for dual views of the samples while mounted on an inverted microscope. https://openminds.ebrains.eu/instances/technique/dualViewInvertedSelectivePlaneIlluminationMicroscopy JSON-LD
echo planar pulse sequence In magnetic resonance imaging, a 'echo-planar pulse sequence' is a contrasting technique where each radio frequency field (RF) excitation is followed by a train of gradient echoes with different spatial encoding allowing for very rapid scanning. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Physics_of_magnetic_resonance_imaging#Echo-planar_imaging)] https://openminds.ebrains.eu/instances/technique/echoPlanarPulseSequence JSON-LD
electrocardiography Electrocardiography is a non-invasive technique used to record the electrical activity of a heart using electrodes placed on the skin. [adapted from [Wikipedia](https://en.wikipedia.org/wiki/Electrocardiography)] https://openminds.ebrains.eu/instances/technique/electrocardiography JSON-LD
electrocorticography 'Electrocorticography', short ECoG, is an intracranial electroencephalography technique in which electrodes are placed (subdural or epidural) on the exposed surface of the brain to record electrical activity from the cerebral cortex. https://openminds.ebrains.eu/instances/technique/electrocorticography JSON-LD
electroencephalography https://openminds.ebrains.eu/instances/technique/electroencephalography JSON-LD
electromyography https://openminds.ebrains.eu/instances/technique/electromyography JSON-LD
electron microscopy Electron microscopy describes any microscopy technique that uses electrons to generate contrast. https://openminds.ebrains.eu/instances/technique/electronMicroscopy http://uri.interlex.org/tgbugs/uris/readable/technique/electronMicroscopy JSON-LD , Interlex
electron tomography Electron tomography is a microscopy technique that takes a series of images of a thick sample at different angles (tilts) so that tomography can be applied to increase the resolution of the ticker sample. https://openminds.ebrains.eu/instances/technique/electronTomography http://id.nlm.nih.gov/mesh/2018/M0512939 JSON-LD , Interlex
electrooculography https://openminds.ebrains.eu/instances/technique/electrooculography JSON-LD
electroporation A microbiology technique in which an electrical field is applied to cells in order to increase the permeability of the cell membrane. https://openminds.ebrains.eu/instances/technique/electroporation http://uri.interlex.org/tgbugs/uris/readable/technique/electroporation JSON-LD , Interlex
ensemble learning The term 'ensemble learning' refers to a group of techniques that allow the application of a combination of machine-learning methods and agggregate the results of those methods into one output. https://openminds.ebrains.eu/instances/technique/ensembleLearning JSON-LD
enzyme-linked immunosorbent assay The 'enzyme-linked immunosorbent assay' is a commonly used analytical biochemistry assay for the quantitative determination of antibodies, first described by [Engvall and Perlmann (1972)](https://www.jimmunol.org/content/109/1/129.abstract). [adapted from [wikipedia](https://en.wikipedia.org/wiki/ELISA)] https://openminds.ebrains.eu/instances/technique/enzymeLinkedImmunosorbentAssay http://id.nlm.nih.gov/mesh/2018/M0007526 JSON-LD , Interlex
epidermal electrophysiology technique The term 'epidermal electrophysiology technique' describes a subclass of non-invasive electrophysiology techniques where one or several electrodes are placed on the outermost cell layer of an organism (epidermis) to measure electrical properties. https://openminds.ebrains.eu/instances/technique/epidermalElectrophysiologyTechnique JSON-LD
epidural electrocorticography https://openminds.ebrains.eu/instances/technique/epiduralElectrocorticography JSON-LD
epifluorescent microscopy Epifluorescent microscopy comprises all widefield microscopy techniques in which fluorescent molecules of an entire sample are excited through a permanent exposure of a light source of a specific wavelength. https://openminds.ebrains.eu/instances/technique/epifluorescentMicroscopy http://uri.interlex.org/tgbugs/uris/indexes/ontologies/methods/243 JSON-LD , Interlex
extracellular electrophysiology In 'extracellular electrophysiology' electrodes are inserted into living tissue, but remain outside the cells in the extracellular environment to measure or stimulate electrical activity coming from adjacent cells, usually neurons. https://openminds.ebrains.eu/instances/technique/extracellularElectrophysiology JSON-LD
eye movement tracking 'Eye movement tracking' refers to a group of techniques used to measure the eye movement and/or position of a living specimen over a given period of time. https://openminds.ebrains.eu/instances/technique/eyeMovementTracking http://id.nlm.nih.gov/mesh/2018/M0493574 JSON-LD , Interlex
fixation technique Fixation is a technique to preserve specimen permanently as faithfully as possible compared to the living state. https://openminds.ebrains.eu/instances/technique/fixationTechnique JSON-LD , Interlex
fluorescence microscopy Fluorescence microscopy comprises any type of microscopy where the specimen can be made to fluoresce (emit energy as visible light), typically by illuminating it with light of specific wavelengths. https://openminds.ebrains.eu/instances/technique/fluorescenceMicroscopy http://purl.obolibrary.org/obo/CHMO_0000087 JSON-LD , Interlex
focused ion beam scanning electron microscopy Focused ion beam scanning electron microscopy is a serial section scanning electron microscopy technique where a focused ion beam is used to ablate the surface of a specimen. https://openminds.ebrains.eu/instances/technique/focusedIonBeamScanningElectronMicroscopy http://uri.interlex.org/tgbugs/uris/indexes/ontologies/methods/245 JSON-LD , Interlex
functional magnetic resonance imaging https://openminds.ebrains.eu/instances/technique/functionalMagneticResonanceImaging JSON-LD
gene expression measurement https://openminds.ebrains.eu/instances/technique/geneExpressionMeasurement JSON-LD
gene knockin https://openminds.ebrains.eu/instances/technique/geneKnockin JSON-LD
gene knockout https://openminds.ebrains.eu/instances/technique/geneKnockout JSON-LD
general linear modeling https://openminds.ebrains.eu/instances/technique/generalLinearModeling JSON-LD
genetic correlation analysis https://openminds.ebrains.eu/instances/technique/geneticCorrelationAnalysis JSON-LD
genetic risk score A genetic risk score is an estimate of the cumulative contribution of genetic factors to a specific outcome of interest in an individual (Igo et al, 2019). https://openminds.ebrains.eu/instances/technique/geneticRiskScore JSON-LD
genome-wide association study A 'genome-wide association study' is an analysis technique comparing the allele frequencies of all available (or a whole genome representative set of) polymorphic markers in unrelated individuals with a specific symptom or disease condition, and those of healthy controls to identify markers associated with a specific disease or condition. https://openminds.ebrains.eu/instances/technique/genomeWideAssociationStudy http://edamontology.org/topic_3517 JSON-LD , Interlex , Knowledge Space
global signal regression A 'global signal regression' is a denoising technique where the global signal is removed from the time series of each voxel through linear regression. [adapted from: [Murphy & Fox, 2017](https://dx.doi.org/10.1016%2Fj.neuroimage.2016.11.052)] https://openminds.ebrains.eu/instances/technique/globalSignalRegression JSON-LD
Golgi staining 'Golgi staining' includes several silver staining techniques in which fixed tissue is impregnated with silver nitrate and potassium dichromate resulting in the complete staining of some nerve cells while other cells are not stained at all. [adapted from InterLex](http://uri.interlex.org/ilx_0104713) https://openminds.ebrains.eu/instances/technique/GolgiStaining http://uri.neuinfo.org/nif/nifstd/birnlex_2243 JSON-LD , Interlex
gradient-echo pulse sequence In magnetic resonance imaging, a 'gradient-echo pulse sequence' is a contrast generation technique that rapidly induces bulk changes in the spin magnetization of a sample by applying a series of carefully constructed pulses so that the change in the gradient of the magnetic field is maximized, trading contrast for speed (cf. [Hargreaves (2012)](https://doi.org/10.1002/jmri.23742)). https://openminds.ebrains.eu/instances/technique/gradientEchoPulseSequence JSON-LD
Grubbs' test The 'Grubbs test' is a statistical test, first published by [Grubbs (1950)](https://doi.org/10.1214/aoms/1177729885), used to detect outliers in univariate data that are assumed to come from a normally distributed population. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Grubbs%27s_test)] https://openminds.ebrains.eu/instances/technique/GrubbsTest JSON-LD
H&E staining An 'H&E staining' combines the two histological stains hematoxylin and eosin which highlight a large portion of microscopic anatomy in a tissue. It is therefore the most widely used stain in medical and histopathological diagnosis. https://openminds.ebrains.eu/instances/technique/HEStaining JSON-LD
heavy metal negative staining In a 'heavy metal negative staining', a thin and amorphous film of heavy metal salts (e.g. uranyl acetate) is applied on a sample to reveal its structural details for electron microscopy. https://openminds.ebrains.eu/instances/technique/heavyMetalNegativeStaining JSON-LD
hierarchical agglomerative clustering https://openminds.ebrains.eu/instances/technique/hierarchicalAgglomerativeClustering JSON-LD
hierarchical clustering https://openminds.ebrains.eu/instances/technique/hierarchicalClustering JSON-LD
hierarchical divisive clustering https://openminds.ebrains.eu/instances/technique/hierarchicalDivisiveClustering JSON-LD
hierarchical phase-contrast tomography 'Hierarchical phase-contrast tomography' is an X-ray technique which decouple field of view and resolution to image with cellular (micron) resolution [adapted from [UCL HiP-CT webpage](https://mecheng.ucl.ac.uk/hip-ct/)]. https://openminds.ebrains.eu/instances/technique/hierarchicalPhaseContrastTomography JSON-LD
high-density electroencephalography https://openminds.ebrains.eu/instances/technique/highDensityElectroencephalography JSON-LD
high-field functional magnetic resonance imaging https://openminds.ebrains.eu/instances/technique/highFieldFunctionalMagneticResonanceImaging JSON-LD
high-field magnetic resonance imaging https://openminds.ebrains.eu/instances/technique/highFieldMagneticResonanceImaging JSON-LD
high-resolution scanning https://openminds.ebrains.eu/instances/technique/high-resolutionScanning JSON-LD
high-speed video recording https://openminds.ebrains.eu/instances/technique/high-speedVideoRecording JSON-LD
high-throughput scanning 'High-throughput scanning' is a technique for automatic creation of analog or digital images of a large number of samples. https://openminds.ebrains.eu/instances/technique/highThroughputScanning JSON-LD
histochemistry https://openminds.ebrains.eu/instances/technique/histochemistry JSON-LD
Hoechst staining A nuclear-specific staining technique where a Hoechst dye is used. https://openminds.ebrains.eu/instances/technique/HoechstStaining JSON-LD
HPC simulation https://openminds.ebrains.eu/instances/technique/HPCSimulation JSON-LD
ICA based denoising technique An 'ICA based denoising technique' removes independent components from input data to reduce noise while preserving the features of interest in the data. https://openminds.ebrains.eu/instances/technique/ICABasedDenoisingTechnique JSON-LD
image distortion correction 'Image distortion correction' is the general term for any image processing technique correcting optical or perspective aberrations of an image. https://openminds.ebrains.eu/instances/technique/imageDistortionCorrection JSON-LD
image registration An 'image registration' is a process of bringing a set of images into the same coordinate system. https://openminds.ebrains.eu/instances/technique/imageRegistration JSON-LD
immunohistochemistry In 'immunohistochemistry' antigens or haptens are detected and visualized in cells of a tissue sections by exploiting the principle of antibodies binding specifically to antigens in biological tissues. https://openminds.ebrains.eu/instances/technique/immunohistochemistry JSON-LD
immunoprecipitation https://openminds.ebrains.eu/instances/technique/immunoprecipitation JSON-LD
implant surgery https://openminds.ebrains.eu/instances/technique/implantSurgery JSON-LD
in situ hybridisation https://openminds.ebrains.eu/instances/technique/inSituHybridisation JSON-LD
independent component analysis https://openminds.ebrains.eu/instances/technique/independentComponentAnalysis JSON-LD
infrared differential interference contrast video microscopy https://openminds.ebrains.eu/instances/technique/infraredDifferentialInterferenceContrastVideoMicroscopy http://uri.interlex.org/tgbugs/uris/readable/technique/IRDIC JSON-LD , Interlex
injection https://openminds.ebrains.eu/instances/technique/injection JSON-LD
inter-subject analysis https://openminds.ebrains.eu/instances/technique/interSubjectAnalysis JSON-LD
interpolation An 'interpolation' is an analysis technique that delivers estimates for new data points based on a range of a discrete set of known data points. https://openminds.ebrains.eu/instances/technique/interpolation JSON-LD
intra-subject analysis https://openminds.ebrains.eu/instances/technique/intraSubjectAnalysis JSON-LD
intracellular electrophysiology A technique used to measure electrical properties of a single cell, e.g. a neuron. https://openminds.ebrains.eu/instances/technique/intracellularElectrophysiology http://uri.interlex.org/tgbugs/uris/indexes/ontologies/methods/222 JSON-LD , Interlex
intracellular injection https://openminds.ebrains.eu/instances/technique/intracellularInjection JSON-LD
intracranial electroencephalography https://openminds.ebrains.eu/instances/technique/intracranialElectroencephalography JSON-LD
intraperitoneal injection An 'intraperitoneal injection' is the administration of a substance into the peritoneum (abdominal cavity) via a needle or tube. https://openminds.ebrains.eu/instances/technique/intraperitonealInjection JSON-LD
intravenous injection An 'intravenous injection' is the administration of a substance into a vein or veins via a needle or tube. https://openminds.ebrains.eu/instances/technique/intravenousInjection JSON-LD
iontophoresis https://openminds.ebrains.eu/instances/technique/iontophoresis JSON-LD
iontophoretic microinjection https://openminds.ebrains.eu/instances/technique/iontophoreticMicroinjection JSON-LD
k-means clustering 'k-means clustering' is a centroid-based cluster analysis technique that aims to partition n observations into a pre-defined number of k clusters by assigning each observation to the cluster with the nearest mean (centroid). https://openminds.ebrains.eu/instances/technique/k-meansClustering JSON-LD
light microscopy Light microscopy, also referred to as optical microscopy, comprises any type of microscopy technique that uses visible light to generate magnified images of small objects. https://openminds.ebrains.eu/instances/technique/lightMicroscopy http://edamontology.org/topic_3385 JSON-LD , Interlex
light sheet fluorescence microscopy Lightsheet fluorescence microscopy is a fluorescence microscopy technique that uses a thin sheet of light to excite only fluorophores within the plane of illumination. https://openminds.ebrains.eu/instances/technique/lightSheetFluorescenceMicroscopy http://uri.interlex.org/tgbugs/uris/readable/technique/lightSheetMicroscopyFluorescent JSON-LD , Interlex
linear image registration A 'linear image registration' is a process of bringing a set of images into the same coordinate system using linear transformation. https://openminds.ebrains.eu/instances/technique/linearImageRegistration JSON-LD
linear regression A 'linear regression' is an analysis approach for modelling the linear relationship between a scalar response and one or more explanatory variables. https://openminds.ebrains.eu/instances/technique/linearRegression JSON-LD
linear transformation A 'linear transformation' is a linear mathematical function to map coordinates between two different coordinate systems while perserving straight lines. https://openminds.ebrains.eu/instances/technique/linearTransformation JSON-LD
literature mining https://openminds.ebrains.eu/instances/technique/literatureMining JSON-LD
magnetic resonance imaging 'Magnetic resonance imaging' is a medical imaging technique that uses strong magnetic fields, magnetic field gradients, and radio waves to generate images of the anatomy and the physiological processes of the body. https://openminds.ebrains.eu/instances/technique/magneticResonanceImaging JSON-LD , Interlex
magnetic resonance spectroscopy https://openminds.ebrains.eu/instances/technique/magneticResonanceSpectroscopy JSON-LD
magnetoencephalography 'Magnetoencephalography' is a noninvasive neuroimaging technique for studying brain activity by recording magnetic fields produced by electrical currents occurring naturally in the brain, using very sensitive magnetometers. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Magnetoencephalography)] https://openminds.ebrains.eu/instances/technique/magnetoencephalography http://uri.interlex.org/tgbugs/uris/indexes/ontologies/methods/163 JSON-LD , Interlex
manifold learning 'manifold learning' refers to a group of machine learning algorithms for non-linear dimensionality reduction of high-dimensionalty data. https://openminds.ebrains.eu/instances/technique/manifoldLearning JSON-LD
Mann–Whitney U test The 'Mann–Whitney U test' is a nonparametric test of the null hypothesis that, for randomly selected values X and Y from two populations, the probability of X being greater than Y is equal to the probability of Y being greater than X. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Mann%E2%80%93Whitney_U_test)] https://openminds.ebrains.eu/instances/technique/MannWhitneyUTest JSON-LD
mass spectrometry https://openminds.ebrains.eu/instances/technique/massSpectrometry JSON-LD
mass univariate analysis A 'mass univariate analysis' is the statistical analysis of a massive number of simultaneously measured dependent variables via the performance of univariate hypothesis tests. https://openminds.ebrains.eu/instances/technique/massUnivariateAnalysis JSON-LD
maximum likelihood estimation technique 'Maximum likelihood estimation' is a statistical analysis technique that estimates the parameters of an assumed probability distribution for some observed data by maximizing a likelihood function so that, under the assumed statistical model, the observed data is most probable. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Maximum_likelihood_estimation)] https://openminds.ebrains.eu/instances/technique/maximumLikelihoodEstimation JSON-LD
maximum probability projection https://openminds.ebrains.eu/instances/technique/maximumProbabilityProjection JSON-LD
meta-analysis https://openminds.ebrains.eu/instances/technique/metaAnalysis JSON-LD
meta-analytic connectivity modeling https://openminds.ebrains.eu/instances/technique/metaAnalyticConnectivityModeling JSON-LD
metadata parsing https://openminds.ebrains.eu/instances/technique/metadataParsing JSON-LD
microtome sectioning A technique used to cut specimen in thin slices using a microtome. https://openminds.ebrains.eu/instances/technique/microtomeSectioning http://uri.interlex.org/tgbugs/uris/indexes/ontologies/methods/212 JSON-LD , Interlex
model-based stimulation artifact correction The 'model-based stimulation artifact correction' is a model-based analysis technique for removing stimulation artifacts from intracranial electroencephalography signals to uncover the cortico-cortical evoked potentials caused by the stimulation (cf. [Trebaul et al. (2016)](https://doi.org/10.1016/j.jneumeth.2016.03.002)). https://openminds.ebrains.eu/instances/technique/modelBasedstimulationArtifactCorrection JSON-LD
morphometric analysis https://openminds.ebrains.eu/instances/technique/morphometricAnalysis JSON-LD
morphometry https://openminds.ebrains.eu/instances/technique/morphometry JSON-LD
motion correction 'Motion correction' is the general term for any preprocessing analysis technique used to correct for motion artifacts in imaging time-series. https://openminds.ebrains.eu/instances/technique/motionCorrection JSON-LD
movement tracking 'Movement tracking' refers to a group of techniques used to measure the movement and/or position of an object, specimen, or anatomical parts of a specimen over a given period of time. https://openminds.ebrains.eu/instances/technique/movementTracking JSON-LD
multi-compartment modeling https://openminds.ebrains.eu/instances/technique/multi-compartmentModeling JSON-LD
multi-electrode extracellular electrophysiology https://openminds.ebrains.eu/instances/technique/multiElectrodeExtracellularElectrophysiology JSON-LD
multi-scale individual component clustering 'multi-scale individual component clustering' is a multi-scale, unsupervised cluster analysis technique to group individual, independent components of a single-object/single-subject independent component analysis (ICA) from an object-pool/subject-pool (cf. [Naveau et al, 2012](https://doi.org/10.1007/s12021-012-9145-2)). https://openminds.ebrains.eu/instances/technique/multi-scaleIndividualComponentClustering JSON-LD
multi-voxel pattern analysis A 'multi-voxel pattern analysis' is considered as a supervised classification problem where a classifier attempts to capture the relationships between spatial patterns of functional magnetic resonance imaging activity and experimental conditions ([Mahmoudi et al., 2012](https://doi.org/10.1155/2012/961257), [Davatzikos et al., 2005](https://doi.org/10.1016/j.neuroimage.2005.08.009)). https://openminds.ebrains.eu/instances/technique/multiVoxelPatternAnalysis JSON-LD
multiple linear regression A 'multiple linear regression' is a linear approach for modelling the relationship between a scalar response and multiple explanatory variables. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Linear_regression)] https://openminds.ebrains.eu/instances/technique/multipleLinearRegression JSON-LD
multiple whole cell patch clamp https://openminds.ebrains.eu/instances/technique/multipleWholeCellPatchClamp JSON-LD
myelin staining A technique used to selectively alter the appearance of myelin (sheaths) that surround the nerve cell axons. https://openminds.ebrains.eu/instances/technique/myelinStaining http://uri.neuinfo.org/nif/nifstd/birnlex_2248 JSON-LD , Interlex
neuromorphic simulation https://openminds.ebrains.eu/instances/technique/neuromorphicSimulation JSON-LD
Nissl staining The term 'Nissl staining' refers to various basic dyes (e.g., aniline, thionine, cresyl violet) that selectively label negatively charged molecules (e.g., DNA, RNA) and are therefore typically used to highlight important structural features of cell bodies. https://openminds.ebrains.eu/instances/technique/NisslStaining JSON-LD
nonlinear image registration A 'nonlinear image registration' is a process of bringing a set of images into the same coordinate system using nonlinear transformation. https://openminds.ebrains.eu/instances/technique/nonlinearImageRegistration JSON-LD
nonlinear transformation A 'nonlinear transformation' is a mathematical function to map coordinates between two different coordinate systems, not perserving straight lines. https://openminds.ebrains.eu/instances/technique/nonlinearTransformation JSON-LD
nonrigid image registration A 'nonrigid image registration' is a process of bringing a set of images into the same coordinate system using nonrigid transformation. https://openminds.ebrains.eu/instances/technique/nonrigidImageRegistration JSON-LD
nonrigid motion correction https://openminds.ebrains.eu/instances/technique/nonrigidMotionCorrection JSON-LD
nonrigid transformation A 'nonrigid transformation' is a specific linear transformation using combinations of rotations, translations, reflections, scaling, shearing, and perspective projections to map coordinates between two coordinate spaces. https://openminds.ebrains.eu/instances/technique/nonrigidTransformation JSON-LD
nucleic acid extraction 'Nucleic acid extraction' refers to a group of techniques that all separate nucleic acids from proteins and lipids using three major processes: isolation, purification, and concentration. https://openminds.ebrains.eu/instances/technique/nucleicAcidExtraction JSON-LD
nuisance regression 'Nuisance regression' is an image processing technique which seeks to attenuate non-neural BOLD fluctuations from measurable noise sources such as scanner drift and head motion, as well as periodic physiological signals. [adapted from [Hallquist et al. 2013](https://doi.org/10.1016%2Fj.neuroimage.2013.05.116)] https://openminds.ebrains.eu/instances/technique/nuisanceRegression JSON-LD
optogenetic inhibition Optogenetic inhibition is a genetic technique in which the activity of specific neuron populations is decreased using light of a particular wavelength. This can be achieved by expressing light-sensitive ion channels, pumps or enzymes specifically in the target neurons. https://openminds.ebrains.eu/instances/technique/optogeneticInhibition JSON-LD
oral administration In an 'oral administration' a substance is taken through the mouth. https://openminds.ebrains.eu/instances/technique/oralAdministration JSON-LD
organ extraction https://openminds.ebrains.eu/instances/technique/organExtraction JSON-LD
patch clamp https://openminds.ebrains.eu/instances/technique/patchClamp JSON-LD
pathway analysis A 'pathway analysis' refers to a group of techniques that aim to discover what biological themes, and which biomolecules, are crucial to understand biological pathways of (typically) high-throughput biological data (adapted from [García-Campos et al., 2015](https://doi.org/10.3389/fphys.2015.00383)). https://openminds.ebrains.eu/instances/technique/pathwayAnalysis http://edamontology.org/operation_3928 JSON-LD , Interlex
performance profiling https://openminds.ebrains.eu/instances/technique/performanceProfiling JSON-LD
perfusion fixation technique Perfusion fixation is a fixation technique to preserve specimen permanently as faithfully as possible compared to the living state by using the vascular system to distribute fixatives throughout the tissue. https://openminds.ebrains.eu/instances/technique/perfusionFixationTechnique JSON-LD
perfusion technique Perfusion is a technique to distribute fluid through the circulatory system or lymphatic system to an organ or a tissue. https://openminds.ebrains.eu/instances/technique/perfusionTechnique JSON-LD , Interlex
perturbational complexity index measurement https://openminds.ebrains.eu/instances/technique/perturbationalComplexityIndexMeasurement JSON-LD
phase synchronization analysis A 'phase synchronization analysis' detects and quantifies synchronization between two time series. https://openminds.ebrains.eu/instances/technique/phaseSynchronizationAnalysis JSON-LD
phase-contrast x-ray imaging 'Phase-contrast x-ray imaging' is a general term for different x-ray techniques that use changes in the phase of an x-ray beam passing through an object leading to images with improved soft tissue contrast without the application of a contrast medium. (adapted from [Wikipedia](https://en.wikipedia.org/wiki/Phase-contrast_X-ray_imaging)) https://openminds.ebrains.eu/instances/technique/phaseContrastXRayImaging JSON-LD
phase‐contrast x‐ray computed tomography 'Phase-contrast x-ray computed tomography' is a non-invasive x-ray imaging technique for three-dimensional observation of organic matter without application of a contrast medium ([Momose, Takeda, and Itai (1995)](https://doi.org/10.1063/1.1145931)). https://openminds.ebrains.eu/instances/technique/phaseContrastXRayComputedTomography JSON-LD
photoactivation https://openminds.ebrains.eu/instances/technique/photoactivation JSON-LD
photoinactivation https://openminds.ebrains.eu/instances/technique/photoinactivation JSON-LD
photoplethysmography Photoplethysmography is a non-invasive technique to optically detect blood volume changes in the micro-vascular bed of tissue by measuring the transmissive absorption and/or the reflection of light by the skin. https://openminds.ebrains.eu/instances/technique/photoplethysmography http://id.nlm.nih.gov/mesh/2018/M0026056 JSON-LD , Interlex
polarized light microscopy Polarized light microscopy comprises all optical microscopy techniques involving polarized light. https://openminds.ebrains.eu/instances/technique/polarizedLightMicroscopy http://id.nlm.nih.gov/mesh/2018/M0013816 JSON-LD , Interlex
population receptive field mapping https://openminds.ebrains.eu/instances/technique/populationReceptiveFieldMapping JSON-LD
positron emission tomography https://openminds.ebrains.eu/instances/technique/positronEmissionTomography JSON-LD
pressure injection Pressure injection uses either air compression or mechanical pressure to eject a substance from a micropipette (from Veith et al., 2016; J.Vis.Exp. (109):53724; doi: 10.3791/53724). https://openminds.ebrains.eu/instances/technique/pressureInjection JSON-LD
primary antibody staining https://openminds.ebrains.eu/instances/technique/primaryAntibodyStaining JSON-LD
principal component analysis A 'principal component analysis' is a statistical technique for reducing the dimensionality of a dataset by linearly transforming the data into a new coordinate system where (most of) the variation in the data can be described with fewer dimensions than the initial data. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Principal_component_analysis)] https://openminds.ebrains.eu/instances/technique/principalComponentAnalysis JSON-LD
probabilistic anatomical parcellation technique https://openminds.ebrains.eu/instances/technique/probabilisticAnatomicalParcellationTechnique JSON-LD
probabilistic diffusion tractography https://openminds.ebrains.eu/instances/technique/probabilisticDiffusionTractography JSON-LD
pseudo-continuous arterial spin labeling https://openminds.ebrains.eu/instances/technique/pseudoContinuousArterialSpinLabeling JSON-LD
psychological testing 'Psychological testing' is a psychometric measurement to evaluate a person's response to a psychological test according to carefully prescribed guidelines. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Psychological_testing)] https://openminds.ebrains.eu/instances/technique/psychologicalTesting JSON-LD
pupillometry Pupillometry is the measurement of minute fluctuations in pupil diameter in response to a stimulus. https://openminds.ebrains.eu/instances/technique/pupillometry JSON-LD
qualitative analysis 'Qualitative analysis' uses subjective judgment to analyze data based on non-quantifiable information. The resulting data are typically nonnumerical. https://openminds.ebrains.eu/instances/technique/qualitativeAnalysis JSON-LD
quantification https://openminds.ebrains.eu/instances/technique/quantification JSON-LD
quantitative analysis https://openminds.ebrains.eu/instances/technique/quantitativeAnalysis JSON-LD
quantitative magnetic resonance imaging https://openminds.ebrains.eu/instances/technique/quantitativeMagneticResonanceImaging JSON-LD
receptive field mapping In 'receptive field mapping' a distinct set of physiological stimuli is used to evoke a sensory neuronal response in specific organisms to define its respective sensory space (receptive field). https://openminds.ebrains.eu/instances/technique/receptiveFieldMapping JSON-LD
reconstruction technique A 'reconstruction technique' is able to re-build, re-assemble, re-create, or re-imagine something by applying (often mathematical) principles to physical evidence. https://openminds.ebrains.eu/instances/technique/reconstructionTechnique JSON-LD
reporter gene based expression measurement https://openminds.ebrains.eu/instances/technique/reporterGeneBasedExpressionMeasurement JSON-LD
reporter protein based expression measurement https://openminds.ebrains.eu/instances/technique/reporterProteinBasedExpressionMeasurement JSON-LD
retinotopic mapping In 'retinotopic mapping' the retina is repeatedly stimulated in such a way that the response of neurons, particularly within the visual stream, can be mapped to the location of the stimulus on the retina. https://openminds.ebrains.eu/instances/technique/retinotopicMapping JSON-LD
retrograde tracing Retrograde tracing is a technique used to trace neural connections from their point of termination (the synapse) to their source (the cell body). https://openminds.ebrains.eu/instances/technique/retrogradeTracing JSON-LD
rigid image registration A 'rigid image registration' is a process of bringing a set of images into the same coordinate system using rigid transformation. https://openminds.ebrains.eu/instances/technique/rigidImageRegistration JSON-LD
rigid motion correction https://openminds.ebrains.eu/instances/technique/rigidMotionCorrection JSON-LD
rigid transformation A 'rigid transformation' is a specific linear transformation using combinations of rotations, translations, and reflections to map coordinates between two coordinate spaces, leaving the oject congruent. https://openminds.ebrains.eu/instances/technique/rigidTransformation JSON-LD
RNA sequencing 'RNA sequencing' refers to a group of techniques that are used to (directly or indirectly) determine the order of nucleotides (nucleic acid sequence) in RNA. https://openminds.ebrains.eu/instances/technique/RNASequencing http://purl.obolibrary.org/obo/OBI_0001177 JSON-LD , Interlex
rule-based modeling https://openminds.ebrains.eu/instances/technique/rule-basedModeling JSON-LD
scanning electron microscopy Scanning electron microscopy is a microscopy technique to produce images of a specimen by scanning the surface with focused beam of electrons. https://openminds.ebrains.eu/instances/technique/scanningElectronMicroscopy http://uri.interlex.org/tgbugs/uris/readable/technique/scanningElectronMicroscopy JSON-LD , Interlex
scattered light imaging https://openminds.ebrains.eu/instances/technique/scatteredLightImaging JSON-LD
SDS-digested freeze-fracture replica labeling https://openminds.ebrains.eu/instances/technique/SDSDigestedFreezeFractureReplicaLabeling JSON-LD
secondary antibody staining https://openminds.ebrains.eu/instances/technique/secondaryAntibodyStaining JSON-LD
seed-based correlation analysis https://openminds.ebrains.eu/instances/technique/seed-basedCorrelationAnalysis JSON-LD
semantic anchoring https://openminds.ebrains.eu/instances/technique/semanticAnchoring JSON-LD
semiquantitative analysis An analysis technique which constitutes or involves less than quantitative precision. https://openminds.ebrains.eu/instances/technique/semiquantitativeAnalysis JSON-LD
serial block face scanning electron microscopy Serial block face scanning electron microscopy is a serial section scanning electron microscopy technique where an ultramicrotome is used to remove the surface layer of a specimen. https://openminds.ebrains.eu/instances/technique/serialBlockFaceScanningElectronMicroscopy JSON-LD
serial section transmission electron microscopy Serial section transmission electron microscopy is a microscopy technique in which a beam of electrons is transmitted through multiple successive slices of a volumetric sample to produce images of the slices (e.g. for later 3D reconstruction). https://openminds.ebrains.eu/instances/technique/serialSectionTransmissionElectronMicroscopy JSON-LD
Shapiro-Wilk test The 'Shapiro–Wilk test' is a statistical test of normality of a complete sample, first described by [Shapiro and Wilk (1965)](https://doi.org/10.1093/biomet/52.3-4.591). [adapted from [wikipedia](https://en.wikipedia.org/wiki/Shapiro%E2%80%93Wilk_test)] https://openminds.ebrains.eu/instances/technique/ShapiroWilkTest JSON-LD
signal filtering technique 'Signal filtering' is a signal processing technique used to remove or suppress unwanted components or features (e.g., certain frequencies) from a measured signal. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Filter_(signal_processing))] https://openminds.ebrains.eu/instances/technique/signalFilteringTechnique http://uri.interlex.org/tgbugs/uris/indexes/ontologies/methods/151 JSON-LD , Interlex
signal processing technique 'Signal processing' refers to a class of analysis techniques used to improve transmission, storage efficiency and subjective quality as well as to emphasize or detect components of interest in a measured signal. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Signal_processing)] https://openminds.ebrains.eu/instances/technique/signalProcessingTechnique http://uri.interlex.org/tgbugs/uris/readable/technique/sigproc JSON-LD , Interlex
silver staining A technique where the appearance of biological subcellular targets (e.g. proteins, RNA or DNA) is selectively alter by use of silver. https://openminds.ebrains.eu/instances/technique/silverStaining http://uri.neuinfo.org/nif/nifstd/nlx_152217 JSON-LD , Interlex
simulation https://openminds.ebrains.eu/instances/technique/simulation JSON-LD
single cell RNA sequencing https://openminds.ebrains.eu/instances/technique/singleCellRNASequencing JSON-LD
single electrode extracellular electrophysiology https://openminds.ebrains.eu/instances/technique/singleElectrodeExtracellularElectrophysiology JSON-LD
single electrode juxtacellular electrophysiology https://openminds.ebrains.eu/instances/technique/singleElectrodeJuxtacellularElectrophysiology JSON-LD
single gene analysis A 'single gene analysis' is a genetic test (sequencing technique) to check for any genetic changes in a specific gene. https://openminds.ebrains.eu/instances/technique/singleGeneAnalysis JSON-LD
single nucleotide polymorphism detection 'Single nucleotide polymorphism detection' refers to a group of techniques that are used to scan for new polymorphisms and to determine the allele(s) of a known polymorphism in target sequences (adapted from [Kwok and Chen, 2003](https://doi.org/10.21775/cimb.005.043)). https://openminds.ebrains.eu/instances/technique/singleNucleotidePolymorphismDetection http://edamontology.org/operation_0484 JSON-LD , Interlex
slice timing correction 'Slice timing correction' is a preprocessing technique applied to functional magnetic resonance image data in order to correct for temporal offsets between 2D image slices during the data acquisition. [adapted from [Parker and Razlighi, 2019](https://doi.org/10.3389/fnins.2019.00821)] https://openminds.ebrains.eu/instances/technique/sliceTimingCorrection JSON-LD
sodium MRI 'Sodium MRI' is a specialised magnetic resonance imaging technique that uses strong magnetic fields, magnetic field gradients, and radio waves to generate images of the distribution of sodium in the body. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Sodium_MRI)] https://openminds.ebrains.eu/instances/technique/sodiumMRI JSON-LD
sonography https://openminds.ebrains.eu/instances/technique/sonography JSON-LD
Spearman's rank-order correlation The 'Spearman's rank-order correlation' is the nonparametric version of the Pearson product-moment correlation measuring the strength and direction of association between a set of two ranked variables. [adapted from [Laerd.com](https://statistics.laerd.com/statistical-guides/spearmans-rank-order-correlation-statistical-guide.php)] https://openminds.ebrains.eu/instances/technique/SpearmansRankOrderCorrelation JSON-LD
spectral power auto-segmentation technique A 'spectral power auto-segmentation technique' makes use of the power spectrum along the time axis of individual pixels or voxels in an image to automatically generate a segmentation. https://openminds.ebrains.eu/instances/technique/spectralPowerAutoSegmentationTechnique JSON-LD
spike sorting 'Spike sorting' is a class of techniques used in the analysis of extracellular electrophysiological data to extract the activity of one or more neurons from the background electrical noise by making use of the typical waveforms action potentials (spikes) create in the recorded neuronal signal. https://openminds.ebrains.eu/instances/technique/spikeSorting JSON-LD , Interlex
spin echo pulse sequence In magnetic resonance imaging, a 'spin echo pulse sequence' is a contrast generation technique that induces bulk changes in the spin magnetization of a sample by applying sequential pulses of resonant electromagnetic waves at different angles (cf. [Fonseca (2013)](https://doi.org/10.5772/53693)). https://openminds.ebrains.eu/instances/technique/spinEchoPulseSequence JSON-LD
stereoelectroencephalography In 'stereoelectroencephalography' depth electrodes (typically linear electrode arrays) are stereotactically implanted in the brain of a subject in order to record or stimulate electrographic activity of otherwise inaccessible brain regions. [cf. [wikipedia](https://en.wikipedia.org/wiki/Stereoelectroencephalography), or [Gholipour et al. 2020](https://doi.org/10.1016/j.clineuro.2019.105640)] https://openminds.ebrains.eu/instances/technique/stereoelectroencephalography JSON-LD
stereology An imaging assay that is used for the three-dimensional interpretation of planar sections of materials or tissues. https://openminds.ebrains.eu/instances/technique/stereology http://uri.interlex.org/tgbugs/uris/indexes/ontologies/methods/79 JSON-LD , Interlex
stereotactic surgery https://openminds.ebrains.eu/instances/technique/stereotacticSurgery JSON-LD
stochastic online matrix factorization 'Stochastic online matrix factorization' is a matrix-factorization algorithm that scales to input matrices with both huge number of rows and columns [(Mensch et al., 2018)](https://doi.org/10.1109/TSP.2017.2752697). https://openminds.ebrains.eu/instances/technique/stochasticOnlineMatrixFactorization JSON-LD
structural covariance analysis https://openminds.ebrains.eu/instances/technique/structuralCovarianceAnalysis JSON-LD
structural neuroimaging https://openminds.ebrains.eu/instances/technique/structuralNeuroimaging JSON-LD
subcutaneous injection An 'subcutenous injection' is the administration of a substance under all the layers of the skin via a needle or tube. https://openminds.ebrains.eu/instances/technique/subcutaneousInjection JSON-LD
subdural electrocorticography https://openminds.ebrains.eu/instances/technique/subduralElectrocorticography JSON-LD
subliminal stimulation 'Subliminal stimulation' is a technique providing any sensory stimuli below an individual's threshold for conscious perception (adapted from [wikipedia](https://en.wikipedia.org/wiki/Subliminal_stimuli)) https://openminds.ebrains.eu/instances/technique/subliminalStimulation JSON-LD
subliminal visual simulation 'Subliminal visual simulation' is a technique providing visual stimuli below an indivdual's threshold for conscious perception [adapted from [wikipedia](https://en.wikipedia.org/wiki/Subliminal_stimuli)] https://openminds.ebrains.eu/instances/technique/subliminalVisualSimulation JSON-LD
support-vector machine classifier A 'support-vector machine classifier' is a supervised machine learning technique that analyzes data for classification. https://openminds.ebrains.eu/instances/technique/supportVectorMachineClassifier JSON-LD
support-vector regression algorithm A 'Support-Vector Regression Algorithm' is a supervised machine learning technique used to estimate the relationship between a dependent and a number of independent variables. https://openminds.ebrains.eu/instances/technique/supportVectorMachineRegression JSON-LD
surface projection https://openminds.ebrains.eu/instances/technique/surfaceProjection JSON-LD
SWITCH immunohistochemistry https://openminds.ebrains.eu/instances/technique/SWITCHImmunohistochemistry JSON-LD
T1 pulse sequence In magnetic resonance imaging, a 'T1 pulse sequence' is a contrasting technique that allows the magnetization of the specimen or object to recover (spin-lattice relaxation) before measuring the magnetic resonance signal by changing the repetition time. [adapted from [wikipedia](https://en.wikipedia.org/wiki/MRI_sequence)] https://openminds.ebrains.eu/instances/technique/T1PulseSequence JSON-LD
T2 pulse sequence In magnetic resonance imaging, a 'T2 pulse sequence' is a contrasting technique that allows the magnetization of the specimen or object to decay (spin-spin relaxation) before measuring the magnetic resonance signal by changing the echo time. [adapted from [wikipedia](https://en.wikipedia.org/wiki/MRI_sequence)] https://openminds.ebrains.eu/instances/technique/T2PulseSequence JSON-LD
TDE clearing https://openminds.ebrains.eu/instances/technique/TDEClearing JSON-LD
temporal filtering 'Temporal filtering' is a functional image signal processing technique that aims to remove or attenuate frequencies that vary along the time axis of the raw signal. [adapted from [Wikibooks](https://en.wikibooks.org/wiki/Neuroimaging_Data_Processing/Processing/Steps/Temporal_Filtering)] https://openminds.ebrains.eu/instances/technique/temporalFiltering JSON-LD
tetrode extracellular electrophysiology https://openminds.ebrains.eu/instances/technique/tetrodeExtracellularElectrophysiology JSON-LD
time-of-flight magnetic resonance angiography 'Time-of-flight magnetic resonance angiography' is a non-invasive, non-contrast-enhanced technique used to visualize both arterial and venous vessels with high spatial resolution. Note: it provides no information regarding directionality nor flow velocity quantification. [adapted from: [Ferreira and Ramalho, 2013](https://doi.org/10.1002/9781118434550.ch7)] https://openminds.ebrains.eu/instances/technique/time-of-flightMagneticResonanceAngiography JSON-LD
Timm's staining A technique used to selectively visualize a variety of metals (e.g. zinc, copper, iron) in biological tissue based on sulphide-precipitation of metals in the tissue. https://openminds.ebrains.eu/instances/technique/TimmsStaining http://uri.neuinfo.org/nif/nifstd/birnlex_2248 JSON-LD , Interlex
tissue clearing https://openminds.ebrains.eu/instances/technique/tissueClearing JSON-LD
tract tracing https://openminds.ebrains.eu/instances/technique/tractTracing JSON-LD
tractography https://openminds.ebrains.eu/instances/technique/tractography JSON-LD
transcardial perfusion fixation technique Transcardial perfusion fixation is a technique to distribute fixatives throughout tissue via the heart. https://openminds.ebrains.eu/instances/technique/transcardialPerfusionFixationTechnique JSON-LD
transcardial perfusion technique Transcardial perfusion is a technique to distribute fluid throughout tissue via the heart. https://openminds.ebrains.eu/instances/technique/transcardialPerfusionTechnique http://uri.interlex.org/tgbugs/uris/indexes/ontologies/methods/167 JSON-LD , Interlex
transformation A 'transformation' is a mathematical function to map coordinates between two different coordinate systems. https://openminds.ebrains.eu/instances/technique/transformation JSON-LD
transmission electron microscopy Transmission electron microscopy is a microscopy technique in which a beam of electrons is transmitted through a specimen to produce an image. https://openminds.ebrains.eu/instances/technique/transmissionElectronMicroscopy JSON-LD
two-photon fluorescence microscopy Two-photon fluorescence microscopy is a fluorescence microscopy technique for living tissue which is based on the simultaneous excitation by two photons with longer wavelength than the emitted light. https://openminds.ebrains.eu/instances/technique/twoPhotonFluorescenceMicroscopy http://uri.interlex.org/tgbugs/uris/readable/technique/twoPhoton JSON-LD , Interlex
ultra high-field functional magnetic resonance imaging 'Ultra high-field functional magnetic resonance imaging' comprises all functional MRI techniques conducted with a MRI scanner with a magnetic field strength equal or above 7 Tesla. https://openminds.ebrains.eu/instances/technique/ultraHighFieldFunctionalMagneticResonanceImaging JSON-LD
ultra high-field magnetic resonance imaging 'Ultra high-field magnetic resonance imaging' comprises all structural MRI techniques conducted with a MRI scanner with a magnetic field strength equal or above 7 Tesla. https://openminds.ebrains.eu/instances/technique/ultraHighFieldMagneticResonanceImaging JSON-LD
ultra high-field magnetic resonance spectroscopy 'Ultra high-field magnetic resonance spectroscopy' comprises all MRS techniques conducted with a MRI scanner with a magnetic field strength equal or above 7 Tesla. https://openminds.ebrains.eu/instances/technique/ultraHighFieldMagneticResonanceSpectroscopy JSON-LD
vibratome sectioning https://openminds.ebrains.eu/instances/technique/vibratomeSectioning JSON-LD
video annotation https://openminds.ebrains.eu/instances/technique/videoAnnotation JSON-LD
video tracking https://openminds.ebrains.eu/instances/technique/videoTracking JSON-LD
video-oculography https://openminds.ebrains.eu/instances/technique/video-oculography JSON-LD
virus-mediated transfection https://openminds.ebrains.eu/instances/technique/virus-mediatedTransfection JSON-LD
voltage clamp 'Voltage clamp' comprises all experimental techniques in which the membrane potential (voltage) is constantly changed to a desired value by adding the necessary current to the cell. https://openminds.ebrains.eu/instances/technique/voltageClamp JSON-LD
voltage sensitive dye imaging 'Voltage sensitive dye imaging' is an experimental technique to measure neuronal population activity from in vivo brains or live brain slices by transducing changes in the cell membrane potential into changes of fluorescence emmission by an employed exogenous chemical agent. https://openminds.ebrains.eu/instances/technique/voltageSensitiveDyeImaging JSON-LD
voxel-based morphometry https://openminds.ebrains.eu/instances/technique/voxel-basedMorphometry JSON-LD
Ward clustering https://openminds.ebrains.eu/instances/technique/WardClustering JSON-LD
weighted correlation network analysis Weighted correlation network analysis is a widely used data mining method for studying networks based on pairwise correlations between variables. While it can be applied to most high-dimensional data sets, it has been most widely used in genomic applications. [adopted from: [wikipedia](https://en.wikipedia.org/wiki/Weighted_correlation_network_analysis)] https://openminds.ebrains.eu/instances/technique/weightedCorrelationNetworkAnalysis JSON-LD
whole cell patch clamp 'Whole cell patch clamp' is a patch clamp technique where the pipette is sealed onto a cell membrane applying enough suction to rupture the membrane patch in order to provide access from the interior of the pipette to the intracellular space of the cell. https://openminds.ebrains.eu/instances/technique/wholeCellPatchClamp JSON-LD
whole genome sequencing 'Whole genome sequencing' is a genetic test (sequencing technique) to determine the entire, or nearly the entire, DNA sequence of an organism's genome at a single time. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Whole_genome_sequencing)] https://openminds.ebrains.eu/instances/technique/wholeGenomeSequencing http://id.nlm.nih.gov/mesh/2018/M000621306 JSON-LD , Interlex
widefield fluorescence microscopy 'Widefield fluorescence microscopy' comprises all microscopy techniques in which fluorescent molecules of an entire sample are excited through a permanent exposure of a light source of a specific wavelength. https://openminds.ebrains.eu/instances/technique/widefieldFluorescenceMicroscopy JSON-LD
z-score analysis The 'z-score analysis' is a statistical normalization technique where the z-score is calculated by subtracting the population mean from an individual raw score (observed data point) and dividing the difference by the population standard deviation. [adapted from [Wikipedia](https://en.wikipedia.org/wiki/Standard_score)] https://openminds.ebrains.eu/instances/technique/zScoreAnalysis JSON-LD