MolecularEntity

https://openminds.ebrains.eu/controlledTerms/MolecularEntity

part of controlledTerms in version v1 - view as JSON Schema

Required properties are highlighted in bold
propertyvalue
name*descriptiontypeinstruction
name Word or phrase that constitutes the distinctive designation of a being or thing. string Controlled term originating from a defined terminology.
definition Short, but precise statement of the meaning of a word, word group, sign or a symbol. string Enter one sentence for defining this term.
description Longer statement or account giving the characteristics of someone or something. string Enter a short text describing this term.
interlexIdentifier Persistent identifier for a term registered in the InterLex project. string (format: iri) Enter the internationalized resource identifier (IRI) pointing to the integrated ontology entry in the InterLex project.
knowledgeSpaceLink Persistent link to an encyclopedia entry in the Knowledge Space project. string (format: iri) Enter the internationalized resource identifier (IRI) pointing to the wiki page of the corresponding term in the KnowledgeSpace.
preferredOntologyIdentifier Persistent identifier of a preferred ontological term. string (format: iri) Enter the internationalized resource identifier (IRI) pointing to the preferred ontological term.
synonym Words or expressions used in the same language that have the same or nearly the same meaning in some or all senses. array (1 - n) of type:
string		 Enter one or several synonyms (including abbreviations) for this controlled term.
*This is the simplified property name - within a metadata instance of this schema (JSON-LD) the properties are extended to map to the openMINDS vocabulary namespace ("https://openminds.ebrains.eu/vocab/PROPERTY_NAME").
instances
nameID Preferred ontology identifier
5-HT transporter The 5-HT transporter is a type of monoamine transporter protein that transports the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) from the synaptic cleft back to the presynaptic neuron. https://openminds.ebrains.eu/instances/molecularEntity/5-HTTransporter http://purl.obolibrary.org/obo/PR_000015189 JSON-LD , Knowledge Space
5-HT1A receptor The 5-HT1A receptor is a subtype of serotonin receptor group (5-HT receptors) that bind the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). https://openminds.ebrains.eu/instances/molecularEntity/5-HT1AReceptor http://uri.neuinfo.org/nif/nifstd/nifext_5890 JSON-LD , Interlex , Knowledge Space
5-HT1B receptor The 5-HT1B receptor is a subtype of serotonin receptor group (5-HT receptors) that bind the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). https://openminds.ebrains.eu/instances/molecularEntity/5-HT1BReceptor http://uri.neuinfo.org/nif/nifstd/nifext_6386 JSON-LD , Interlex , Knowledge Space
5-HT2 receptor The 5-HT2 receptor is a subtype of serotonin receptor group (5-HT receptors) that bind the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). https://openminds.ebrains.eu/instances/molecularEntity/5-HT2Receptor http://id.nlm.nih.gov/mesh/2018/M0018621 JSON-LD , Interlex
5-HT2A receptor The 5-HT2A receptor is a subtype of serotonin receptor group (5-HT receptors) that bind the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). https://openminds.ebrains.eu/instances/molecularEntity/5-HT2AReceptor http://uri.neuinfo.org/nif/nifstd/nifext_6741 JSON-LD , Interlex , Knowledge Space
5-HT4 receptor The 5-HT4 receptor is a subtype of serotonin receptor group (5-HT receptors) that bind the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). https://openminds.ebrains.eu/instances/molecularEntity/5-HT4Receptor http://uri.neuinfo.org/nif/nifstd/nifext_6151 JSON-LD , Interlex , Knowledge Space
A1 receptor The adenosine A1 receptor is a subtype of the adenosine receptor group that bind adenosine as endogenous ligand. https://openminds.ebrains.eu/instances/molecularEntity/A1Receptor http://uri.neuinfo.org/nif/nifstd/nifext_5717 JSON-LD , Interlex
A2A receptor The adenosine A2A receptor is a subtype of the adenosine receptor group that bind adenosine as endogenous ligand. https://openminds.ebrains.eu/instances/molecularEntity/A2AReceptor http://uri.neuinfo.org/nif/nifstd/nifext_7727 JSON-LD , Interlex , Knowledge Space
acetylcholine Acetylcholine in vertebrates is the major neurotransmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. https://openminds.ebrains.eu/instances/molecularEntity/acetylcholine http://uri.neuinfo.org/nif/nifstd/sao185580330 JSON-LD , Interlex
Alexa Fluor 594 Alexa Fluor 594' is a fluorochrome/fluorescent dye used to stain biological specimens. https://openminds.ebrains.eu/instances/molecularEntity/AlexaFluor594 http://purl.obolibrary.org/obo/CHEBI_51248 JSON-LD , Knowledge Space
alpha-1 receptor The alpha-1 receptor is a subclass of the adrenoceptor group that bind epinephrine or norepinephrine as endogenous ligands. https://openminds.ebrains.eu/instances/molecularEntity/alpha-1Receptor JSON-LD
alpha-2 receptor The alpha-2 receptor is a subclass of the adrenoceptor group that bind epinephrine or norepinephrine as endogenous ligands. https://openminds.ebrains.eu/instances/molecularEntity/alpha-2Receptor JSON-LD
alpha-4 beta-2 receptor The alpha-4 beta-2 receptor belongs to the family of nicotinic acetylcholine receptors that respond to the neurotransmitter acetylcholine as endogenous ligand. This subtype is located in the brain, where activation yields post- and presynaptic excitation. https://openminds.ebrains.eu/instances/molecularEntity/alpha-4Beta-2Receptor http://id.nlm.nih.gov/mesh/2018/M0356600 JSON-LD , Interlex
AMPA receptor The AMPA receptors belong to the class of ionotropic glutamate receptors and mediate fast synaptic transmission in the central nervous system (CNS). https://openminds.ebrains.eu/instances/molecularEntity/AMPAReceptor http://uri.neuinfo.org/nif/nifstd/nifext_5251 JSON-LD , Interlex , Knowledge Space
anterograde tracer An anterograde tracer is a molecule that is taken up by neurons (e.g., by viral transfection mechanisms, by other cell internalization mechanisms or passive diffusion) and transported towards the axon terminals. It is used for anterograde tract tracing studies in the nervous system. https://openminds.ebrains.eu/instances/molecularEntity/anterogradeTracer http://purl.obolibrary.org/obo/NLXMOL_1012002 JSON-LD , Knowledge Space
Beta-Amyloid 40 Amyloid beta peptide with carboxyterminal variant ending at residual Val40. https://openminds.ebrains.eu/instances/molecularEntity/Beta-Amyloid40 http://uri.neuinfo.org/nif/nifstd/nlx_13181 JSON-LD , Interlex , Knowledge Space
biomarker A substance used as an indicator of a biological state, most commonly disease. https://openminds.ebrains.eu/instances/molecularEntity/biomarker http://uri.neuinfo.org/nif/nifstd/nlx_mol_20090517 JSON-LD , Interlex
biotinylated dextran amine A 'biotinylated dextran amine' is an organic compound which is used as an anterograde and retrograde neuroanatomical tracer. https://openminds.ebrains.eu/instances/molecularEntity/biotinylatedDextranAmine http://id.nlm.nih.gov/mesh/2018/M0205506 JSON-LD , Interlex
brain-derived neurotrophic factor The 'brain-derived neurotrophic factor' is a protein that, in humans, is encoded by the BDNF gene. [adapted from [wikipedia](https://en.wikipedia.org/wiki/Brain-derived_neurotrophic_factor)] https://openminds.ebrains.eu/instances/molecularEntity/brainDerivedNeurotrophicFactor JSON-LD , Interlex , Knowledge Space
c-FOS c-FOS is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos. https://openminds.ebrains.eu/instances/molecularEntity/c-FOS https://ncimeta.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&code=C0314702 JSON-LD , Knowledge Space
calbindin Calbindin is a calcium-binding protein. https://openminds.ebrains.eu/instances/molecularEntity/calbindin http://uri.neuinfo.org/nif/nifstd/nlx_mol_1006006 JSON-LD , Interlex , Knowledge Space
calcium calmodulin protein kinase II The 'calcium calmodulin protein kinase II' is a protein with a core domain architecture consisting of a Protein kinase domain and a C-terminal Calcium/calmodulin dependent protein kinase II Association domain. https://openminds.ebrains.eu/instances/molecularEntity/calciumCalmodulinProteinKinaseII http://purl.obolibrary.org/obo/PR_000003197 JSON-LD , Interlex , Knowledge Space
calcium calmodulin protein kinase II alpha chain The 'calcium calmodulin protein kinase II alpha chain' is a calcium/calmodulin-dependent protein kinase type II chain that is a translation product of the human CAMK2A gene or a 1:1 ortholog thereof. https://openminds.ebrains.eu/instances/molecularEntity/calciumCalmodulinProteinKinaseIIAlphaChain http://purl.obolibrary.org/obo/PR_000003199 JSON-LD , Knowledge Space
calretinin Calretinin is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. https://openminds.ebrains.eu/instances/molecularEntity/calretinin http://uri.neuinfo.org/nif/nifstd/nifext_5717 JSON-LD , Interlex , Knowledge Space
cholecystokinin Cholecystokinin is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. https://openminds.ebrains.eu/instances/molecularEntity/cholecystokinin http://uri.neuinfo.org/nif/nifstd/nifext_5068 JSON-LD , Interlex
choline acetyltransferase Choline acetyltransferase is a synthetic enzyme that catalyzes the formation of acetylcholine from acetyl-CoA and choline https://openminds.ebrains.eu/instances/molecularEntity/cholineAcetyltransferase http://uri.neuinfo.org/nif/nifstd/sao722953401 JSON-LD , Interlex
cyclic adenosine monophosphate Cyclic adenosine monophosphate is a second messenger important in many biological processes. https://openminds.ebrains.eu/instances/molecularEntity/cyclicAdenosineMonophosphate http://purl.obolibrary.org/obo/CHEBI_17489 JSON-LD , Interlex , Knowledge Space
D1 receptor The D1 receptor is a subtype of the dopamine receptor group that primarily binds the neurotransmitter dopamine as endogenous ligand. The D1 receptor is the most abundant kind of dopamine receptor in the central nervous system. https://openminds.ebrains.eu/instances/molecularEntity/D1Receptor http://uri.neuinfo.org/nif/nifstd/nifext_5845 JSON-LD , Interlex , Knowledge Space
D2 receptor The D2 receptor is a subtype of the dopamine receptor group that primarily binds the neurotransmitter dopamine as endogenous ligand. https://openminds.ebrains.eu/instances/molecularEntity/D2Receptor http://uri.neuinfo.org/nif/nifstd/nifext_5833 JSON-LD , Interlex , Knowledge Space
DAB DAB is a chemically and thermodynamically stable derivative of benzidine. https://openminds.ebrains.eu/instances/molecularEntity/DAB http://purl.obolibrary.org/obo/CHEBI_90994 JSON-LD , Interlex , Knowledge Space
dopamine Dopamine is one of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. https://openminds.ebrains.eu/instances/molecularEntity/dopamine http://purl.obolibrary.org/obo/CHEBI_18243 JSON-LD , Interlex , Knowledge Space
dopamine transporter A 'dopamine transporter' is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol. https://openminds.ebrains.eu/instances/molecularEntity/dopamineTransporter http://purl.obolibrary.org/obo/PR_000015188 JSON-LD , Interlex , Knowledge Space
dynorphin Dynorphin belongs to a class of opioid peptides that arise from the precursor protein prodynorphin. Dynorphins bind to the kappa opioid receptor. https://openminds.ebrains.eu/instances/molecularEntity/dynorphin http://uri.neuinfo.org/nif/nifstd/nifext_5097 JSON-LD , Interlex
enkephalin Enkephalin is a pentapeptide involved in regulating nociception in the body. https://openminds.ebrains.eu/instances/molecularEntity/enkephalin http://uri.neuinfo.org/nif/nifstd/nifext_5096 JSON-LD , Interlex
epibatidine Epibatidine is a chlorinated alkaloid that binds to nicotinic and muscarinic acetylcholine receptors with high affinity. https://openminds.ebrains.eu/instances/molecularEntity/epibatidine http://uri.neuinfo.org/nif/nifstd/nlx_chem_20090204 JSON-LD , Interlex
excitatory amino acid transporter The excitatory amino acid transporters are a subclass of glutamate transporters that remove glutamate from the synaptic cleft and extrasynaptic sites via glutamate reuptake into glial cells and neurons. https://openminds.ebrains.eu/instances/molecularEntity/excitatoryAminoAcidTransporter JSON-LD
excitatory amino acid transporter 1 The excitatory amino acid transporter 1 belongs to the EAAT familiy. It is predominantly expressed in the plasma membrane removing glutamate from the extracellular space, but was also localized in the inner mitochondrial membrane as part of the malate-aspartate shuttle. https://openminds.ebrains.eu/instances/molecularEntity/excitatoryAminoAcidTransporter1 http://purl.obolibrary.org/obo/PR_0000149744 JSON-LD , Interlex , Knowledge Space
excitatory amino acid transporter 2 The excitatory amino acid transporter 2 belongs to the EAAT familiy. It clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system and is responsible for over 90% of glutamate reuptake within the brain. https://openminds.ebrains.eu/instances/molecularEntity/excitatoryAminoAcidTransporter2 http://purl.obolibrary.org/obo/PR_000014973 JSON-LD , Interlex , Knowledge Space
excitatory amino acid transporter 3 The excitatory amino acid transporter 3 belongs to the EAAT familiy transporting glutamate across plasma membranes in neurons. It can also transport aspartate and plays a role in the neuronal cysteine uptake. https://openminds.ebrains.eu/instances/molecularEntity/excitatoryAminoAcidTransporter3 http://purl.obolibrary.org/obo/PR_000014972 JSON-LD , Interlex , Knowledge Space
excitatory amino acid transporter 4 The excitatory amino acid transporter 4 belongs to the EAAT familiy. It is expressed predominantly in the cerebellum, has high affinity for the excitatory amino acids L-aspartate and L-glutamate. https://openminds.ebrains.eu/instances/molecularEntity/excitatoryAminoAcidTransporter4 http://purl.obolibrary.org/obo/PR_000014977 JSON-LD , Interlex , Knowledge Space
excitatory amino acid transporter 5 The excitatory amino acid transporter 5 belongs to the EAAT familiy. It is expressed predominantly in the retina, has high affinity for the excitatory amino acid L-glutamate. https://openminds.ebrains.eu/instances/molecularEntity/excitatoryAminoAcidTransporter5 http://purl.obolibrary.org/obo/PR_000014978 JSON-LD , Knowledge Space
flumazenil Flumazenil is a selective GABAA receptor antagonist that binds to the benzodiazepine recognition site on the GABAA/benzodiazepine receptor complex. https://openminds.ebrains.eu/instances/molecularEntity/flumazenil http://purl.obolibrary.org/obo/CHEBI_5103 JSON-LD , Interlex
fluorescent microspheres Fluorescent microspheres are non-toxic, non-biologically reactive small polymers embedded with fluorescent dye which are used in medical imaging, as markers for fluorescent microscopy and as standards for flow cytometry fluorescent cell sorting. https://openminds.ebrains.eu/instances/molecularEntity/fluorescentMicrospheres JSON-LD
Fluoro-Emerald Fluoro-Emerald is a fluorescent dextran derivative (dextran, fluorescein, 10,000 MW) used for tracing studies in the nervous system. https://openminds.ebrains.eu/instances/molecularEntity/Fluoro-Emerald JSON-LD
Fluoro-Gold Fluoro-Gold is a fluorescent dye that is used as a retrograde tracer in tract tracing studies. https://openminds.ebrains.eu/instances/molecularEntity/Fluoro-Gold http://uri.neuinfo.org/nif/nifstd/nlx_30125 JSON-LD , Interlex , Knowledge Space
Fluoro-Ruby Fluoro-Ruby is a fluorescent dextran derivative (dextran, tetramethylrhodamine, 10,000 MW) used for retrograde tracing studies in the nervous system. https://openminds.ebrains.eu/instances/molecularEntity/Fluoro-Ruby http://uri.neuinfo.org/nif/nifstd/nlx_65982 JSON-LD , Interlex , Knowledge Space
GABA receptor The GABA receptors are a group of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA) as endogenous ligand. https://openminds.ebrains.eu/instances/molecularEntity/GABAReceptor http://uri.neuinfo.org/nif/nifstd/nlx_mol_1006001 JSON-LD , Interlex , Knowledge Space
GABA-A receptor The GABA-A receptor is an ionotropic subtype of the GABA receptor class that respond to the neurotransmitter gamma-aminobutyric acid (GABA) as endogenous ligand. https://openminds.ebrains.eu/instances/molecularEntity/GABA-AReceptor JSON-LD , Knowledge Space
GABA-A/BZ The GABA-A/BZ is a distinct binding site for benzodiazepines that is situated at the interface between the α- and γ-subunits of α- and γ-subunit containing GABA-A receptors. https://openminds.ebrains.eu/instances/molecularEntity/GABA-A/BZ JSON-LD
GABA-B receptor The GABA-B receptor is a metabotropic subtype of the GABA receptor class that respond to the neurotransmitter gamma-aminobutyric acid (GABA) as endogenous ligand. https://openminds.ebrains.eu/instances/molecularEntity/GABA-BReceptor http://uri.neuinfo.org/nif/nifstd/nlx_mol_090801 JSON-LD , Interlex
gabazine Gabazine is a competitive and selective GABAA antagonist. https://openminds.ebrains.eu/instances/molecularEntity/gabazine http://id.nlm.nih.gov/mesh/2018/M0142643 JSON-LD , Interlex
galanin Galanin is a biologically active neuropeptide, encoded by the GAL gene, that is widely distributed in the central and peripheral nervous systems and the endocrine system. https://openminds.ebrains.eu/instances/molecularEntity/galanin http://uri.neuinfo.org/nif/nifstd/nifext_5074 JSON-LD , Interlex , Knowledge Space
glutamate Glutamate is the carboxylate anion of glutamic acid; and the major excitatory neurotransmitter in the central nervous system of vertebrates, the peripheral nervous system of invertebrates. https://openminds.ebrains.eu/instances/molecularEntity/glutamate http://uri.neuinfo.org/nif/nifstd/sao1744435799 JSON-LD , Interlex , Knowledge Space
glutamate transporter The glutamate transporters are a class of transporter proteins that can move the neurotransmitter glutamate across membranes. https://openminds.ebrains.eu/instances/molecularEntity/glutamateTransporter http://uri.neuinfo.org/nif/nifstd/sao1399894198 JSON-LD , Interlex , Knowledge Space
glycine transporter 2 The glycine transporter 2 is a member of the Na+ and Cl−-coupled transporter family SLC6 that recaptures the inhibitory transmitter glycine in the spinal cord and brainstem. https://openminds.ebrains.eu/instances/molecularEntity/glycineTransporter2 http://purl.obolibrary.org/obo/PR_000015190 JSON-LD , Knowledge Space
growth factor The 'growth factor' comprises signal molecules that are involved in the control of cell growth and differentiation. https://openminds.ebrains.eu/instances/molecularEntity/growthFactor http://uri.neuinfo.org/nif/nifstd/sao1671627152 JSON-LD , Interlex
histamine Histamine is produced by basophils and mast cells (in connective tissues). It is involved in local immune responses and regulating physiological function in the gut and acts as a neurotransmitter (adapted from Wikipedia). https://openminds.ebrains.eu/instances/molecularEntity/histamine http://uri.neuinfo.org/nif/nifstd/nifext_5016 JSON-LD , Interlex , Knowledge Space
insulin-like growth factor 1 The term 'insulin-like growth factor' names a set of proteins with high sequence similarity to insulin that are part of a complex system that cells use to communicate with their physiologic environment. [adpated from [wikipedia](https://en.wikipedia.org/wiki/Insulin-like_growth_factor)] https://openminds.ebrains.eu/instances/molecularEntity/insulinLikeGrowthFactor1 JSON-LD , Interlex , Knowledge Space
intrabody An 'intrabody' is an antibody that works within the cell to bind an intracellular protein. https://openminds.ebrains.eu/instances/molecularEntity/intrabody JSON-LD
ionotropic glutamate receptor Ionotropic glutamate receptors are a class of ligand-gated ion channels that are activated by the neurotransmitter glutamate as endogenous ligand. https://openminds.ebrains.eu/instances/molecularEntity/ionotropicGlutamateReceptor http://uri.neuinfo.org/nif/nifstd/nlx_mol_20090501 JSON-LD , Interlex , Knowledge Space
iperoxo Iperoxo is an organic chemical molecule that is used as a muscarinic M2 receptor agonist. https://openminds.ebrains.eu/instances/molecularEntity/iperoxo http://id.nlm.nih.gov/mesh/2018/M000598130 JSON-LD , Interlex
isoflurane Isoflurane is a stable, non-explosive inhalation anesthetic, relatively free from significant side effects. https://openminds.ebrains.eu/instances/molecularEntity/isoflurane http://purl.obolibrary.org/obo/CHEBI_6015 JSON-LD , Interlex , Knowledge Space
JNK MAP kinase scaffold protein 2 The JNK MAP kinase scaffold protein 2 is a protein that is a translation product of the human MAPK8IP2 gene or a 1:1 ortholog thereof. https://openminds.ebrains.eu/instances/molecularEntity/JNKMapKinaseScaffoldProtein2 http://purl.obolibrary.org/obo/PR_000010161 JSON-LD , Knowledge Space
kainate receptor The kainate receptors belong to the class of ionotropic glutamate receptors that can be involved in excitatory neurotransmission (postsynaptic) as well as inhibitory neurotransmission (presynaptic). https://openminds.ebrains.eu/instances/molecularEntity/kainateReceptor http://uri.neuinfo.org/nif/nifstd/nifext_5252 JSON-LD , Interlex , Knowledge Space
kallikrein-related peptidase 8 The kallikrein-related peptidase 8 is a protein that is a translation product of the mouse Klk1b8 gene or a 1:1 ortholog thereof. https://openminds.ebrains.eu/instances/molecularEntity/kallikrein-relatedPeptidase8 http://purl.obolibrary.org/obo/PR_000009614 JSON-LD , Knowledge Space
ketamine Ketamine is a cyclohexanone derivative used for induction of anesthesia. https://openminds.ebrains.eu/instances/molecularEntity/ketamine https://www.drugbank.ca/drugs/DB01221 JSON-LD , Interlex , Knowledge Space
lucifer yellow Lucifer yellow is a fluorescent dye used that it can be readily visualized in both living and fixed cells using a fluorescence microscope. https://openminds.ebrains.eu/instances/molecularEntity/luciferYellow http://id.nlm.nih.gov/mesh/2018/M0068243 JSON-LD , Interlex
M1 receptor The M1 receptor belongs to the family of muscarinic receptors which are activated by acetylcholine as endegenous ligand. It mediates slow excitatory postsynaptic potential in the postganglionic nerve and is also expressed in exocrine glands and in the central nervous system. https://openminds.ebrains.eu/instances/molecularEntity/M1Receptor http://purl.obolibrary.org/obo/PR_000001613 JSON-LD , Interlex , Knowledge Space
M2 receptor The M2 receptor belongs to the family of muscarinic receptors which are activated by acetylcholine as endegenous ligand. It is expressed in cardiac tissues and acts to slow the heart rate to normal after sympathetic nervous system stimulation. https://openminds.ebrains.eu/instances/molecularEntity/M2Receptor http://purl.obolibrary.org/obo/PR_000001614 JSON-LD , Interlex , Knowledge Space
M3 receptor The M3 receptor belongs to the family of muscarinic receptors which are activated by acetylcholine as endegenous ligand. It is expressed in many glands, in lungs, and in the smooth muscles of blood vessels. https://openminds.ebrains.eu/instances/molecularEntity/M3Receptor http://uri.neuinfo.org/nif/nifstd/nifext_6131 JSON-LD , Interlex , Knowledge Space
medetomidine Medetomidine is a synthetic drug used as both a surgical anesthetic and analgesic. https://openminds.ebrains.eu/instances/molecularEntity/medetomidine http://purl.obolibrary.org/obo/CHEBI_48552 JSON-LD , Interlex , Knowledge Space
metabotropic glutamate receptor Metabotropic glutamate receptors are active through an indirect metabotropic process and respond to glutamate as endogenous ligand. https://openminds.ebrains.eu/instances/molecularEntity/metabotropicGlutamateReceptor http://uri.neuinfo.org/nif/nifstd/nlx_mol_20090503 JSON-LD , Interlex , Knowledge Space
metabotropic glutamate receptor 1 The metabotropic glutamate receptor 1 belongs to group I of the MGluR family. https://openminds.ebrains.eu/instances/molecularEntity/metabotropicGlutamateReceptor1 http://uri.neuinfo.org/nif/nifstd/nlx_mol_20090504 JSON-LD , Interlex
metabotropic glutamate receptor 2 The metabotropic glutamate receptor 2 belongs to group II of the MGluR family. When activated by its endogenous ligand glutamate, it inhibits the emptying of vesicular contents at the presynaptic terminal of glutamatergic neurons. https://openminds.ebrains.eu/instances/molecularEntity/metabotropicGlutamateReceptor2 http://uri.neuinfo.org/nif/nifstd/nlx_mol_20090505 JSON-LD , Interlex , Knowledge Space
metabotropic glutamate receptor 3 The metabotropic glutamate receptor 3 belongs to group II of the MGluR family. When activated by its endogenous ligand glutamate, it inhibits the emptying of vesicular contents at the presynaptic terminal of glutamatergic neurons. https://openminds.ebrains.eu/instances/molecularEntity/metabotropicGlutamateReceptor3 http://uri.neuinfo.org/nif/nifstd/nlx_mol_20090506 JSON-LD , Interlex , Knowledge Space
metabotropic glutamate receptor 5 The metabotropic glutamate receptor 5 belongs to group I of the MGluR family. https://openminds.ebrains.eu/instances/molecularEntity/metabotropicGlutamateReceptor5 http://uri.neuinfo.org/nif/nifstd/nlx_mol_20090508 JSON-LD , Interlex
muscimol Muscimol is a potent and selective orthosteric agonist for the GABAA receptors and displays sedative-hypnotic, depressant and hallucinogenic psychoactivity https://openminds.ebrains.eu/instances/molecularEntity/muscimol http://id.nlm.nih.gov/mesh/2018/M0014231 JSON-LD , Interlex
neurobiotin Neurobiotin is a biotin derivative with moleular weight 286 kDa that can be used as an anterograde and retrograde tracer in the nervous system. https://openminds.ebrains.eu/instances/molecularEntity/neurobiotin http://uri.neuinfo.org/nif/nifstd/nlx_157299 JSON-LD , Interlex , Knowledge Space
neuroligin-3 Neuroligin-3 is a protein that is a translation product of the NLGN3 gene or a 1:1 ortholog thereof. https://openminds.ebrains.eu/instances/molecularEntity/neuroligin-3 http://purl.obolibrary.org/obo/PR_000011256 JSON-LD , Interlex , Knowledge Space
neuronal nuclear antigen Neuronal nuclear antigen is a 46/48KD DNA-binding, neuron-specific protein found in nuclei which is present in most vertebrate CNS and PNS neuronal cell types. https://openminds.ebrains.eu/instances/molecularEntity/neuronalNuclearAntigen http://uri.neuinfo.org/nif/nifstd/nlx_152221 JSON-LD , Interlex
neurotrophic factor The 'neurotrophic factor' is a family of biomolecules that support growth, survival, and differentiation of both developing and mature neurons. https://openminds.ebrains.eu/instances/molecularEntity/neurotrophicFactor JSON-LD
NMDA receptor The NMDA receptors belong to the class of ionotropic glutamate receptors which can be activated with glutamate and glycine with a voltage-dependent current flow. The blockage of the activated channel through extracellular magnesium (Mg2+) and zinc (Zn2+) ions can only be removed when the neuron is sufficiently depolarized. https://openminds.ebrains.eu/instances/molecularEntity/NMDAReceptor http://uri.neuinfo.org/nif/nifstd/nifext_5250 JSON-LD , Interlex , Knowledge Space
parvalbumin Parvalbumin is a calcium-binding albumin protein with low molecular weight (typically 9-11 kDa). https://openminds.ebrains.eu/instances/molecularEntity/parvalbumin http://uri.neuinfo.org/nif/nifstd/nifext_6 JSON-LD , Interlex , Knowledge Space
vesicular glutamate transporter The vesicular glutamate transporters are a subclass of glutamate transporters that move glutamate from the cell cytoplasm into synaptic vesicles. https://openminds.ebrains.eu/instances/molecularEntity/vesicularGlutamateTransporter JSON-LD
vesicular glutamate transporter 1 The vesicular glutamate transporter 1 belongs to the VGLUT family. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. https://openminds.ebrains.eu/instances/molecularEntity/vesicularGlutamateTransporter1 http://purl.obolibrary.org/obo/PR_000014963 JSON-LD , Interlex , Knowledge Space
vesicular glutamate transporter 2 The vesicular glutamate transporter 2 belongs to the VGLUT family. It mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. https://openminds.ebrains.eu/instances/molecularEntity/vesicularGlutamateTransporter2 http://purl.obolibrary.org/obo/PR_000014962 JSON-LD , Interlex , Knowledge Space
vesicular glutamate transporter 3 The vesicular glutamate transporter 3 belongs to the VGLUT family. It transports the neurotransmitter glutamate into synaptic vesicles before it is released into the synaptic cleft. https://openminds.ebrains.eu/instances/molecularEntity/vesicularGlutamateTransporter3 http://purl.obolibrary.org/obo/PR_000014964 JSON-LD , Knowledge Space