The Human Brain Project Brain Simulation Platform¶
The Brain Simulation Platform is part of the Human Brain Project (HBP) Platform ecosystem. It aims at providing scientists with powerful tools to reconstruct and simulate scaffold models of brain and brain tissue in a data-driven fashion. Its development is embedded in Subproject 6 of the HBP, where a tight co-design loop between science and engineering ensures the required substantial technical and scientific innovations.
As a result, the unique functionality of the Platform allows novel questions to be addressed, which could previously not be researched.
- Getting started
- HPC Status Monitor
- Online Use Cases
- Molecular level
- Calculate protein-protein bimolecular association rate constants with webSDA
- Analyse the results of a Brownian dynamics (BD) simulation for calculating protein-protein association rate constants
- Calculate the electrostatic potential of a protein from its atomic structure
- Compare the electrostatic potentials surrounding a set of protein isoforms with multipipsa
- Compare a specific region of the electrostatic potentials surrounding a set of protein isoforms with multipipsa
- Identify potential protein binding sites by comparing the electrostatic potentials of a set of protein isoforms
- Predict protein interaction surface with the ARDOCK server
- Preparing a protein to run an atomistic Molecular Dynamics simulation
- Preparing a protein-ligand complex to run an atomistic Molecular Dynamics simulation
- Small molecule force field parametrization for atomistic Molecular Dynamics simulations
- Subcellular level
- Trace Analysis
- Morphology Analysis
- Single Cell Building
- Circuit Building
- Single Cell In Silico Experiments
- Small Circuit In Silico Experiments
- Brain area circuit in silico experiments
- HBP Validation Framework
- Highly Integrated Workflows
- NEST Desktop
- Molecular level
- Official Documents
- Reference documentation for Platform components